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KMID : 1130620090050020097
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Journal of Clinical Neurology
2009 Volume.5 No. 2 p.97 ~ p.100
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Stroke Mimicking Encephalopathy as an Initial Manifestation of Diffuse Large B-Cell Lymphoma
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Kim Jeong-Min
Jung Keun-Hwa
Lee Soon-Tae
Park Hee-Kwon
Chu Kon
Roh Jae-Kyu
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Abstract
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Background :Systemic lymphoma can be difficult to recognize due to its diverse manifestations. Paraneoplastic leukoencephalopathy has rarely been reported in the context of lymphoma.
Case Report : We report a 45-year-old man with systemic lymphoma whose initial manifestation was sudden-onset leukoencephalopathy, mimicking stroke. This patient, who was eventually diagnosed with diffuse large B-cell lymphoma, initially presented with sudden cognitive impairment and gait disturbance. Radiological studies suggested a paraneoplastic leukoencephalopathy. Chemotherapy for lymphoma resulted in clinical and radiological improvement.
ConClusion :The presented case indicates that diffuse large B-cell lymphoma may initially appear as a treatable leukoencephalopathy.
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KEYWORD
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lymphoma, cerebral infarction, paraneoplastic, leukoencephalopathy
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